HematoLogics, Inc. is a diagnostic service laboratory established in 1995 and is built on a long history of research. Its principals and staff, who have decades of training and experience, invented many of the techniques that are now standard in the field:
- Over 30 years experience in flow cytometry, starting with the first FACS instrument at Stanford in 1973 [1-3]
- Invented multi-color immunofluorescence and multi-angle light scatter [4-6]
- Described the antigenic patterns expressed during normal hematopoietic cell development, and defined both lineage and maturation of cells in erythroid, myeloid, and lymphoid lineages [7-18]
- Identified human progenitor cells and the hematopoietic stem cell [19-23]
- Developed correction for blood contamination of bone marrow specimens [24]
- Developed techniques, including CD45 vs. SSC (right angle light scatter) gating for separation of distinct populations in bone marrow [13, 25-28]
- Showed that tumors express normal antigens in abnormal relationships, allowing the detection of residual leukemia based on “difference from normal” [30-33]
- Developed and fine-tuned techniques for minimal disease detection even in the absence of a diagnostic specimen [34-39]
- Advanced the use of flow cytometry for diagnosis and determination of prognostic outcome in MDS [40-46]
- Pioneered the use of cell sorting in confirmation of minimal residual disease [39, 46-48]
HematoLogics, Inc. combines unique expertise in multi-dimensional flow cytometry, tumor cell sorting, cytogenetics, and molecular genetics with a broad understanding of hematopoiesis and clinical knowledge to provide you with the information you need. Our Retrospect DNA Archiving™ service offers yet one more approach for monitoring your patient for residual disease and determination of relapse.